BDBM338837 US9751886, Compound 2

SMILES C[C@]1(Cn2nncc2C(N)=N1)c1cc(NC(=O)c2ccc(cn2)C#N)ccc1F

InChI Key InChIKey=XIOGEDRAOXMYRT-IBGZPJMESA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 338837   

TargetBeta-secretase 2(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM338837(US9751886, Compound 2)
Affinity DataIC50:  5.37nMAssay Description:This assay is a Fluorescence Resonance Energy Transfer Assay (FRET) based assay. The substrate for this assay contains the ¿Swedish¿ Lys-Met/Asn-Leu ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 2(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM338837(US9751886, Compound 2)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of BACE2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM338837(US9751886, Compound 2)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of BACE2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed